Drug Transmitter by Iontophoresis

Therapeutic Drug Monitoring By Reverse Iontophoresis

Therapeutic molecules possessing distinct pharmacokinetic variation, narrow therapeutic index and concentration dependent therapeutic/adverse effects demand constant monitoring. The current methods for blood sampling are invasive and possess low patient compliance. Human skin, selective and effective membrane to chemical permeation, offers an alternative route for the extraction of endogenous m...

Controlled Transdermal Drug Delivery by Iontophoresis and Ion-exchange Fiber

Kankkunen, T., 2002. Controlled transdermal drug delivery by iontophoresis and ionexchange fiber. Dissertationes Biocentri Viikki Universitatis Helsingiensis 17/2002, pp. 57 ISBN 952-10-0313-8 (print) ISBN 952-10-0314-6 (pdf) ISSN 1239-9469 A common aim in the development of new transdermal devices is the controlled delivery of drugs, so that the rate of drug input into the blood stream is pred...

Prospects of iontophoresis in cardiovascular drug delivery

Clinical benefits, industry interest, regulatory precedence, and strong market potential have made transdermal research the fastest growth area in drug delivery. As most drugs permeate poorly through skin, a major challenge is achieving the therapeutic level by enhancement of permeation rate. Iontophoresis, utilizing a minimal amount of current, is found to affect the skin permeation process dr...

Drug administration with ocular iontophoresis: reaching maturity.

BOTOX delivery by iontophoresis.

We report two patients with severe palmar hyperhidrosis who responded to BOTOX delivered not by injection, the usual method of delivery, but by iontophoresis. The Botulinum molecule has been considered too large for delivery into the skin this way. However, other large peptides, both non-ionic and cationic, have been delivered successfully by this method, so we suspected that BOTOX could in fac...